In December 2014 the club members voted to have the club go dormant December 31, 2014.
Click on Archive above to see the archives for the club.
To visit Orienteering USA, our national organization, click on the following link: www.us.orienteering.org
To visit Cascade Orienteering Club, currently scheduling orienteering events in the Puget Sound area, click on the following link
Today represents the kind of political will and leadership had a need to win the fight tobacco The plan announced.. Campaign for Tobacco-Free Kids issues statement on national tobacco prevention strategy The next is a statement of Matthew L. Myers President, Campaign for Tobacco-Free Kids: The national tobacco prevention strategy announced today by Health and Human Providers Secretary Kathleen Sebelius provides a timely and much-needed shot in the arm for the nation’s efforts to fight tobacco use, the true number one cause of preventable death in the us. Continue reading
The first Phase 2 clinical trial of CERE-120, completed in November 2008, missed its predefined primary endpoint , We are delighted modest benefit was seen in improving motor performance and quality of life in Parkinson’s disease patients, based on statistically significant differences in several secondary endpoints. Even greater improvement was seen following an analysis of all assessed assessed under blinded conditions at 15 to 18 months after treatment, including on the primary measure site . Will is important that new scientific insights into degenerating dopamine neurons in the brains of advanced Parkinson’s patients from CERE-120 – treated patients, the combination of independent causes, with the clinical results, led to important changes in CERE-120 dosing significantly died gained enhance their bioactivity and response to treatment. This revised dosage depends paradigm now both the terminals of the degenerating neurons in a location in the brain as the putamen, and the cell bodies of these neurons, called in a different region of the brain, substantia nigra. – We are pleased controlled Phase controlled Phase 2b trial with with statistical demonstrate the efficacy demonstrate the efficacy of CERE-120 to initiate, said Jeffrey M. Ostrove, president and chief executive officer of Ceregene. We continue to believe, that CERE-120 has the potential to of Parkinson’s disease of Parkinson’s disease and also delay further progression of the disease, and may therefore be a significant advance in the treatment of patients who fail where existing treatments inevitably as their disease progresses. .
About CERE-120 and its potential for treating Parkinson’s diseaseCERE-120 is of an adeno-associated virus vector carrying the gene for neurturin, to repair a naturally occurring protein known damaged and dying dopamine composed secreting neurons, keeping them alive and restoring normal function. Neurturin is a member of the same protein family as glial cell-derived neurotrophic factor . The two molecules have similar pharmacological properties, and both were shown that dopamine neurons in the substantia nigra degenerate degenerate in Parkinson ‘s disease. Degeneration of these neurons is responsible for the large motor impairments of Parkinson’s disease. CERE-120 was. By stereotaxic injection to the terminal regions, ie the ends of the degenerating neurons, in a region of the brain, the putamen is supplied The cell bodies of these same neurons in a different area of the brain is called the substantia nigra and the dosage regimen employed wherein changes in the current phase 2b trial administration calls CERE-120 both the substantia nigra and the putamen. Once CERE-120 provides the brain, it provides stable, long-lasting expression of neurturin in a highly targeted manner. Continue reading
Related StoriesLiposomal sizing and the Coulter principle: an interview with Professor Melvin E. KlegermanPeople with high fitness levels in midlife possess lower annual healthcare costs after age 65Johns Hopkins experts present new healthcare tips from American Heart Association Meeting CoQ10 halved the risk of MACE, with 29 patients in the CoQ10 group reaching the primary endpoint in comparison to 55 individuals in the placebo group (hazard> CoQ10 treated patients had considerably lower cardiovascular mortality> Professor Mortensen stated: CoQ10 may be the first medication to boost survival in chronic center failure since ACE inhibitors and beta blockers more than a decade ago and really should be added to standard heart failing therapy. Continue reading
Adjustments in the expression of genes in the rodents’ brain cells were then examined. Earlier studies that Dr. Ben-Shlomo carried out discovered that the cells’ biological clock is certainly affected, and in today’s research she revealed that the setting of cell division can be harmed and that the transcription of a large number of genes is definitely affected. She states that it is important to remember that those genes showing changes within their expression included genes that are linked to the formation of cancer along with genes that assist in the fight against cancer. Continue reading
Of the 11 evaluable individuals in the scholarly research, 6 partial responses have already been observed up to now. Responses up to now include 4 of 7 sufferers with confirmed T790M negative status. The demonstration will be made offered by Christian Hogg, CEO of Chi-Med stated: Savolitinib is an extremely selective c-Met inhibitor made to get rid of the toxicities experienced by the first wave of c-Met inhibitors within their early development. We have been now happy to find encouraging early efficacy data emerge in non-small cell lung cancers to increase the efficacy currently reported in papillary renal cell carcinoma and colorectal malignancy. Continue reading
Know the Gaming begins the New York Times a few Americans ‘ ‘medical loss ratio ‘, but a bitter struggle, under the new under the new health reform law determine how much insurers must spend on patient care and how much they retain for administration and profits. This is only one of many battles that arise as federal and state regulators to implement reform regulations developed. medication
Risk of mother-to-child HIV transmission rose by genes changea correlation between certain variants of the gene have been discovered, of of a key protein, and the risk of mother-to-child or vertical transmission of HIV. The researchers, writing in BioMed Central Open Access Journal of Translational Medicine examined 300 children born to HIV positive mothers that those who had either of two TLR9 gene variants were significantly more likely to acquire the virus. Continue reading
‘Signed into laws with all of those other health care reform package was a $1 billion therapeutic discovery tax credit aimed at biomedical research projects that show potential in advancing life-saving remedies for unmet medical needs, including malignancy, and in reducing the long-term costs of healthcare and supporting careers’ . The Oklahoman provides: ‘Oklahoma’s fledgling biotechnology firms are hopeful they’ll get a piece of $1 billion in funding, which was tucked into the ongoing healthcare reform bill to greatly help small companies speed development of lifesaving therapies. Altheus Therapeutics Inc. And Selexys Pharmaceuticals Corp. For firms without enough taxable income, the U.S. Treasury will exchange credits for grants of equivalent dollars’ .This article is republished with kind permission from our friends at The Kaiser Family Foundation. Continue reading
We’re forced to allow this business walk, he says. We’re limited from enforcing the law. So heinous is the new policy that a group of ICE brokers has sued the administration over it. From NRO: Among the plaintiffs was wounded after becoming assaulted by an illegal immigrant who had been arrested on a domestic-violence charge in July 2012. When the agent tried to initiate deportation proceedings, ICE superiors purchased him release a the immigrant at no cost, a decision that was predicated on the President’s brand-new immigration guidelines, according to court papers. Continue reading
MD Anderson longstanding relationship with INCAN was developed partly because of the proximity of the centers, and the strong historical, cultural and socio-economic relations between Mexico and Houston show more . In particular, the agreement further population-based studies shared the risk factors for the development of certain cancers among the Mexicans and Mexican-Americans, including the Mexican-American cohort study to understand, the largest study in ever fully on the health of Mexican – American families, currently MD Anderson. Addition, it lays a plan together for a national Mexican tissue bank and faculty education and training related to breast cancer and leukemia, eventually expanding the clinical and translational research projects involve. Among the first effort which is planned from the sister agreement MD Anderson participation in the XXIV Annual Congress INCAN for February 2007 The symposium will highlight achievements in multiple disciplines of oncology and brings faculty from both institutions, projects in clinical, discuss basic and translational research and training. Continue reading
A survey of European doctors by ECDC released in the infectious disease journal Eurosurveillance discovered that one in five experienced seen a lot more than three patients plus some had seen a lot more than ten individuals with an antibiotic-resistant illness in the last six weeks, according to the Telegraph . This article is definitely republished with kind permission from our friends at The Kaiser Family members Foundation. You will see the entire Kaiser Daily Health Policy Statement, search the archives, or join email delivery of in-depth coverage of health policy developments, discussions and debates. Continue reading